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ARTICLE
Year : 2002  |  Volume : 9  |  Issue : 4  |  Page : 210-213

Beta-lactamase detection in nosocomial bacterial pathogens in Lagos, Nigeria


Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Lagos, Nigeria

Correspondence Address:
C N Kesah
Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Lagos
Nigeria
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Source of Support: None, Conflict of Interest: None


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Beta-lactamase production was investigated in 1033 bacterial pathogens--262 gram-positive bacteria, 482 Enterobacteriaceae, 289 non-fermenting bacilli. These were isolated from nosocomial infections in paediatric patients. Beta-lactamase was detected using chromogenic cephalosporin and starch paper methods. More than 80% of the isolates produced the enzyme, which was not detected in enterococci and streptococci. There was no appreciable difference ([symbol: see text] 2 = 5.31, P > 0.05) in the number of Beta-lactamase producers obtained using the two methods. Great caution must be exercised in the therapeutic use of Beta-lactam drugs for nosocomial bacterial infections.


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