Nigerian Postgraduate Medical Journal

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 27  |  Issue : 3  |  Page : 163--170

Spirometric abnormalities following treatment for pulmonary tuberculosis in Ilorin, Nigeria


Olutobi Babatope Ojuawo1, Ademola Emmanuel Fawibe1, Olufemi Olumuyiwa Desalu1, Ayotade Boluwatife Ojuawo2, Adeniyi Olatunji Aladesanmi1, Christopher Muyiwa Opeyemi1, Mosunmoluwa Obafemi Adio1, Alakija Kazeem Salami1 
1 Department of Medicine, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria
2 Department of Paediatrics, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria

Correspondence Address:
Dr. Olutobi Babatope Ojuawo
Department of Medicine, University of Ilorin Teaching Hospital, Ilorin, Kwara State
Nigeria

Background: Pulmonary tuberculosis (PTB) contributes significantly to morbidity and mortality worldwide, and despite microbiological cure for the disease, many patients still demonstrate residual respiratory symptoms and spirometric abnormalities. Aim and Objectives: The study aimed at identifying the prevalence, pattern and factors associated with spirometric abnormalities in patients successfully treated for PTB in Ilorin, Nigeria. Materials and Methods: This was a hospital-based cross-sectional study at the pulmonary outpatient clinics of the University of Ilorin Teaching Hospital and Kwara State Specialist Hospital, Sobi, Ilorin. A total of 308 consenting patients who had been certified microbiologically cured for bacteriologically confirmed PTB in the preceding 3 years had assessment of residual pulmonary symptoms, spirometry and plain chest radiograph. Results: The prevalence of abnormal spirometry following treatment for PTB was 72.1% (confidence interval: 0.6682–0.7695), with restrictive pattern being the predominant abnormality (42.2%). Over half of the patients (56.5%) had at least one residual respiratory symptom. The significant predictors of abnormal spirometry were PTB retreatment (adjusted odds ratio [aOR] = 6.918; P = 0.012), increasing modified Medical Research Council dyspnoea scores (aOR = 7.935; P = 0.008) and increasing radiologic scores (aOR = 4.679; P ≤ 0.001) after treatment. Conclusion: There is significant residual lung function impairment in majority of the individuals successfully treated for PTB in Ilorin. This highlights the need for spirometric assessment and follow-up after treatment.


How to cite this article:
Ojuawo OB, Fawibe AE, Desalu OO, Ojuawo AB, Aladesanmi AO, Opeyemi CM, Adio MO, Salami AK. Spirometric abnormalities following treatment for pulmonary tuberculosis in Ilorin, Nigeria.Niger Postgrad Med J 2020;27:163-170


How to cite this URL:
Ojuawo OB, Fawibe AE, Desalu OO, Ojuawo AB, Aladesanmi AO, Opeyemi CM, Adio MO, Salami AK. Spirometric abnormalities following treatment for pulmonary tuberculosis in Ilorin, Nigeria. Niger Postgrad Med J [serial online] 2020 [cited 2020 Aug 13 ];27:163-170
Available from: http://www.npmj.org/article.asp?issn=1117-1936;year=2020;volume=27;issue=3;spage=163;epage=170;aulast=Ojuawo;type=0