Anticoagulation in pregnant women with mechanical heart valve prostheses: Case reports and a literature review

Philip Alaba Adebola; Folasade A Daniel; Yusuf A Oshodi; Abidoye Gbadegesin; Olagoke K Ale; Ayodeji O Oluwole; Olabode Falase; Mobolaji A Oludara; Jonathan Nwiloh

doi:10.4103/npmj.npmj_344_20

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CASE REPORT

Year : 2021 | Volume : 28 | Issue : 1 | Page : 68-70

Anticoagulation in pregnant women with mechanical heart valve prostheses: Case reports and a literature review

Philip Alaba Adebola¹, Folasade A Daniel¹, Yusuf A Oshodi², Abidoye Gbadegesin², Olagoke K Ale³, Ayodeji O Oluwole⁴, Olabode Falase⁵, Mobolaji A Oludara⁵, Jonathan Nwiloh⁶
¹ Department of Medicine, LASUTH/LASUCOM, Ikeja, Nigeria
² Department of Obstetrics and Gynaecology, LASUTH/LASUCOM, Ikeja, Nigeria
³ Department of Medicine, LUTH/CMUL, Idi-Araba, Lagos, Nigeria
⁴ Department of Obstetrics and Gynaecology, LUTH/CMUL, Idi-Araba, Lagos, Nigeria
⁵ Surgery, LASUTH/LASUCOM, Ikeja, Nigeria
⁶ Department of Surgery, St. Joseph Hospital, Atlanta, Georgia

Correspondence Address:
Dr. Philip Alaba Adebola
Department of Medicine, Division of Cardiology, LASUTH/LASUCOM, Ikeja, Lagos
Nigeria

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/npmj.npmj_344_20

The choice and regimen of anticoagulation therapy in pregnant women with mechanical valve prostheses have always been a daunting task. It is a delicate balance that takes into consideration the risk of thromboembolic complications in the mother and the risk of potential Warfarin embryopathy to the foetus. Medical practice in a low socioeconomic setting also has the peculiar challenge of financial constraints on the part of the patients and difficulties in monitoring the efficacy of anticoagulation therapy. We report our experience in managing two pregnant women with mechanical valve prostheses and review the existing literature on this complex but interesting subject.

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