Nigerian Postgraduate Medical Journal

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 27  |  Issue : 4  |  Page : 285--292

Clinical characteristics, predictors of symptomatic coronavirus disease 2019 and duration of hospitalisation in a cohort of 632 Patients in Lagos State, Nigeria


Olufemi A Erinoso1, Kikelomo Ololade Wright2, Samuel Anya3, Abimbola Bowale4, Olusola Adejumo3, Sunday Adesola4, Bodunrin Osikomaiya5, Bamidele Mutiu6, Babatunde Saka6, Ayodeji Falana4, Disu Ola-Ayinde4, Ephraim I Akase7, Henry Owuna4, Hussein Abdur-Razzaq3, Dayo Lajide3, Oliver Ezechi8, Olusegun Ogboye10, Akin Osibogun9, Akin Abayomi11 
1 Department of Oral and Maxillofacial Surgery, Lagos State University Teaching Hospital, Lagos State, Lagos, Nigeria
2 Department of Community Health and Primary Health Care, Lagos State University Teaching Hospital, Lagos State, Lagos, Nigeria
3 Research Unit, Directorate of Health Planning Research and Statistics Lagos State Ministry of Health, Lagos State, Lagos, Nigeria
4 Infectious Disease Unit, Mainland Hospital, Lagos State, Lagos, Nigeria
5 Lagos State Blood Transfusion Services, Lagos State, Lagos, Nigeria
6 Lagos State Bio-Security Laboratory, Mainland Hospital Yaba, Lagos State, Lagos, Nigeria
7 Department of Medicine, Infectious Disease Unit, Lagos University Teaching Hospital, Lagos State, Lagos, Nigeria
8 Directorate of Research, Institute of Medical Research, Lagos State, Lagos, Nigeria
9 Department of Community and Primary Health, College of Medicine, University of Lagos, Lagos, Nigeria

Correspondence Address:
Dr. Kikelomo Ololade Wright
Department of Community Health and Primary Health Care, Lagos State University Teaching Hospital/ Lagos State University College of Medicine, Lagos
Nigeria

Objective: The clinical spectrum of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is still evolving. This study describes the clinical characteristics and investigates factors that predict symptomatic presentation and duration of hospitalisation in a cohort of coronavirus disease 2019 (COVID-19) patients managed in Lagos, Nigeria. Methodology: This was a retrospective assessment of patients hospitalised with COVID-19 disease in six dedicated facilities in Lagos, Nigeria, between April 1st and May 31st 2020. Participants were individuals with laboratory-confirmed SARS-CoV-2 infection. The outcome measures were presence of symptoms and duration of hospitalisation. Demographic and comorbidity data were also obtained. Statistical analysis was done using STATA 15.0 software, with P < 0.05 being considered statistically significant. Results: A total of 632 cases were analysed. The median age was 40 years (IQR: 30.5–49); male patients accounted for 60.1%. About 63% of patients were asymptomatic at presentation. Among the symptomatic, the most common symptoms were cough (47.4%) and fever (39.7%). The most common comorbidities were hypertension (16.8%) and diabetes (5.2%). The median duration of hospitalisation was 10 days (IQR: 8–14). Comorbidities increased the odds of presenting with symptoms 1.6-fold (P = 0.025) for one comorbidity and 3.2-fold (P = 0.005) for ≥2 comorbidities. Individuals aged ≥50 years were twice as likely to be hospitalised for more than 14 days compared to individuals aged <50 years (P = 0.016). Conclusion: Most individuals had no symptoms with comorbidities increasing the likelihood of symptoms. Older age was associated with longer duration of hospitalisation. Age and comorbidities should be used for COVID-19 triaging for efficient resource allocation.


How to cite this article:
Erinoso OA, Wright KO, Anya S, Bowale A, Adejumo O, Adesola S, Osikomaiya B, Mutiu B, Saka B, Falana A, Ola-Ayinde D, Akase EI, Owuna H, Abdur-Razzaq H, Lajide D, Ezechi O, Ogboye O, Osibogun A, Abayomi A. Clinical characteristics, predictors of symptomatic coronavirus disease 2019 and duration of hospitalisation in a cohort of 632 Patients in Lagos State, Nigeria.Niger Postgrad Med J 2020;27:285-292


How to cite this URL:
Erinoso OA, Wright KO, Anya S, Bowale A, Adejumo O, Adesola S, Osikomaiya B, Mutiu B, Saka B, Falana A, Ola-Ayinde D, Akase EI, Owuna H, Abdur-Razzaq H, Lajide D, Ezechi O, Ogboye O, Osibogun A, Abayomi A. Clinical characteristics, predictors of symptomatic coronavirus disease 2019 and duration of hospitalisation in a cohort of 632 Patients in Lagos State, Nigeria. Niger Postgrad Med J [serial online] 2020 [cited 2020 Nov 28 ];27:285-292
Available from: https://www.npmj.org/article.asp?issn=1117-1936;year=2020;volume=27;issue=4;spage=285;epage=292;aulast=Erinoso;type=0